Ernest McCulloch, Canadian biologist died he was , 84

Ernest Armstrong McCulloch, OC, O.Ont, FRSC was a University of Toronto cellular biologist, best known for demonstrating – with James Till – the existence of stem cells died  he was , 84.

(27 April 1926 – 20 January 2011)

 Biography

McCulloch was born in Toronto, Canada on 21 April 1926, and was educated at Upper Canada College and the University of Toronto.^[3]
Ernest McCulloch received his MD in 1948 from the University of Toronto. Upon graduation, he began his education in research at the Lister Institute in London, England.
In 1957 he joined the newly formed Ontario Cancer Institute where the majority of his research focused on normal blood-formation and leukemia. Together with his colleague, Dr. J.E. Till, McCulloch created the first quantitative, clonal method to identify stem cells and used this technique for pioneering studies on stem cells. His experience in hematology, when combined with Till's experience in biophysics, yielded a novel and productive combination of skills and interests.

In the early 1960s, McCulloch and Till started a series of experiments that involved injecting bone marrow cells into irradiated mice. Visible nodules were observed in the spleens of the mice, in proportion to the number of bone marrow cells injected. Till and McCulloch called the nodules 'spleen colonies', and speculated that each nodule arose from a single marrow cell: perhaps a stem cell.
In later work, Till and McCulloch were joined by graduate student Andy Becker, and demonstrated that each nodule did indeed arise from a single cell. They published their results in Nature in 1963. In the same year, in collaboration with Lou Siminovitch, a trailblazing Canadian molecular biologist, they obtained evidence that these cells were capable of self-renewal, a crucial aspect of the functional definition of stem cells that they had formulated.
A major focus of McCulloch's more recent research has been on cellular and molecular mechanisms affecting the growth of malignant blast stem cells obtained from the blood of patients with Acute Myeloblastic Leukemia.
In 1974, McCulloch became a Fellow of the Royal Society of Canada. In 1988, he became an Officer of the Order of Canada and was made a member of the Order of Ontario in 2006. In 1999, he was made a Fellow of the Royal Society of London. In 2004 McCulloch was inducted into the Canadian Medical Hall of Fame. He holds the distinguished title of University Professor Emeritus at the University of Toronto.
In 2005, he and James Till were awarded the Albert Lasker Award for Basic Medical Research.
The death of McCulloch is greatly mourned by stem cell scientists throughout Canada and the world, many of whom have, with bated breath, been anticipating a Nobel Prize for Till and McCulloch.
McCulloch's work revolutionized cell biology and cancer therapy with the discovery of stem cells in the hematopoietic system.
Their seminal research has been touted as the incipient event that led to revolutionary therapy and survival of leukemia patients worldwide.

Selected publications

• McCulloch, E.A., Till, J.E. (1960) The radiation sensitivity of normal mouse bone marrow cells, determined by quantitative marrow transplantation into irradiated mice. Radiation Research 13(1):115-125. [Link to article]

• Till, J.E., McCulloch, E.A. (1961) A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiation Research 14:213-22. [Link to article]

• Becker, A.J., McCulloch, E.A., Till, J.E. (1963) Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 197:452-4. [Link to article]

• Siminovitch, L., McCulloch, E.A., Till, J.E. (1963) The distribution of colony-forming cells among spleen colonies. Journal of Cellular and Comparative Physiology 62:327-36. [Link to article]

• Till, J.E., McCulloch, E.A., Siminovitch, L. (1964) A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells. Proceedings of the National Academy of Sciences (USA) 51(1):29-36. [Link to article]

• McCulloch, E.A., Siminovitch, L., Till, J.E. (1964) Spleen-colony formation in anemic mice of genotype WWv. Science 144(1620):844-846. [Link to article]

• McCulloch, E.A., Siminovitch, L., Till, J.E., Russell, E.S., Bernstein, S.E. (1965) The cellular basis of the genetically determined hemopoietic defect in anemic mice of genotype Sl/Sld. Blood 26(4):399-410. [Link to article]

• Wu, A.M., Till, J.E., Siminovitch, L., McCulloch, E.A. (1968) Cytological evidence for a relationship between normal hematopoietic colony-forming cells and cells of the lymphoid system. J Exp Med 127(3):455-464. [Link to article]

• Worton, R.G., McCulloch, E.A., Till, J.E. (1969) Physical separation of hemopoietic stem cells differing in their capacity for self-renewal. J Exp Med 130(1):91-103. [Link to article]

• McCulloch, E.A. (2003) Stem cells and diversity. Leukemia 17:1042-48.

• McCulloch, E.A. (2003) Normal and leukemic hematopoietic stem cells and lineages. In: Stem Cells Handbook, Ed. Stewart Sell, Humana Press, Totowa N.J., pp. 119-31.

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F. A. Nettelbeck, American poet died he was , 60.

Fred Arthur Nettelbeck was an American poet died he was , 60.

(November 9, 1950 – January 20, 2011)

In the early 1970s he began work on a long poem that was published in 1979: Bug Death. Bug Death was created using cut-up and collage texts combined with original writing. His literary magazine, This Is Important (1980–1997), published such writers as William S. Burroughs, Wanda Coleman, John M. Bennett, Jack Micheline, Allen Ginsberg, Robin Holcomb, Charles Bernstein, John Giorno, etc. His other publication of note was a Small press mimeo magazine: Throb (1971), publishing Al Masarik, Susan Fromberg Schaeffer, Gerald Locklin, Joel Deutsch, and 'Charles Bukowski answers 10 easy questions'. Nettelbeck's work, publications, and papers are collected in the Ohio State University Avant Writing Collection and the Sackner Archive of Concrete and Visual Poetry. His autobiography is published in Contemporary Authors, Volume 184 (Gale Research). He lived in southern Oregon's Sprague River Valley.

Bibliography

• The Quick & The Dead (Freark Brownelbeck Press 1970)
• No Place Fast (Rough Life Press 1976)
• Destroy All Monsters (Konglomerati 1976) (ISBN 0-916906-26-4)
• Curios (Quark Press 1976)
• Spectator (Drivel Press 1977)
• The Used Future (Alley Island Press 1978)
• Bug Death (Alcatraz Editions 1979)
• Bar Napkin Poems (Clown War 1982)
• Large Talk (road/house 1983)
• Americruiser (Illuminati 1983) (ISBN 0-89897-101-1)
• The Kiss Off (Inkblot 1984)
• Hands On A Mirror (Inkblot 1987) (ISBN 0-934301-09-3)
• Albert Ayler Disappeared (Inkblot 1989) (ISBN 0-934301-29-8)
• Ecosystems Collapsing (Inkblot 1992) (ISBN 0-934301-33-X)
• Everything Written Exists (Lucky Boy Publications 2004)
• Lap Gun Cut (with John M. Bennett) (Luna Bisonte Prods 2006) (ISBN 1892280507)
• Don't Say A Word (Blue Press 2008)
• Taste the (with HEXIT/MjK) (If Year Books 2009)
• Someone Who Loved You (48th Street Press 2010)
• Drinking & Thinking (Blue Press 2010)
• Pesticide Drift (Argotist Ebooks 2010)
• Happy Hour (Four Minutes to Midnight 2010) (ISBN 978-0-9867007-0-5)

Quotes

"Nettelbeck's world (and his picture may be chillingly accurate) is pierced with holes through which we are continually in danger of dropping, or being sucked." -Robert Peters
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Reynolds Price, American author, professor at Duke University died he was , 77.

Reynolds Price was an American novelist, poet, dramatist, essayist and the James B. Duke Professor of English at Duke University died he was , 77.. Apart from English literature, Price had a lifelong interest in ancient languages and Biblical scholarship. He was a member of the American Academy of Arts and Letters.

( February 1, 1933 – January 20, 2011)

  Life

Price was born in Macon, North Carolina, and, after attending public schools of his native state, went to Duke University, where he graduated summa cum laude in 1955. Afterward, he went to Merton College, Oxford for three years as a Rhodes Scholar and wrote a book about life at Oxford, called The Source of Light. While at Oxford Price formed important friendships with the poets W.H Auden and Stephen Spender as well as the biographer Lord David Cecil which helped to spur his writing career on. After his return in 1958, he started teaching at Duke University, which he did till the end of his life.
His first short stories were published in Duke's student literary periodical Archive. Eudora Welty also helped Price get his first couple of books published; she sent one of his early stories, "Michael Egerton" to her own publisher, but Price's first book was not a collection of stories; it was a novel entitled A Long and Happy Life. His other books include his memoir Clear Pictures, and his novels The Tongues of Angels, Blue Calhoun, Kate Vaiden, Roxanna Slade and The Great Circle. The Good Priest's Son, published in 2005, is an account of a 9/11 experience.
In 1984, Price was diagnosed with a malignant spinal tumor. It was treated with radiation therapy, which left him cancer-free but paralyzed from the waist down for the rest of his life. He wrote about his experience in his memoir A Whole New Life: An Illness and a Healing.^[1]
Price died January 20, 2011, after suffering a heart attack five days earlier.

Career

Price was a Southern writer. All his books are set in the South and more particularly in his native North Carolina. Price once replied when asked why he chose to remain in North Carolina: "It's the place about which I have perfect pitch." Price has cited Southern writer Eudora Welty as one of his early influences. He has also been noted for his sexually frank writing, and the ambiguous nature of his own sexuality; Price did not write publicly about being gay until his third memoir, Ardent Spirits: Leaving Home, Coming Back, published in 2009. He began teaching at Duke shortly after completing his Rhodes Scholarship in the late 1950s. For more than forty years Price taught a class on Milton, and his former students included the writers Josephine Humphreys and Anne Tyler, along with the actress Annabeth Gish.
Price is a favorite author of Bill Clinton, who invited him to dinner at the White House early in his first term. Price wrote the lyrics to two songs by James Taylor: "Copperline" and "New Hymn". Price received numerous literary honors, including the National Book Critics Circle Award, the William Faulkner Foundation Award, and was a finalist for the Pulitzer Prize for his memoir Clear Pictures (1989). He was also a member of the American Academy and Institute of Arts and Letters. Price's book, Feasting The Heart (2000), is a collection of controversial and personal essays, originally broadcast to great acclaim on National Public Radio's All Things Considered.

Books

• A Long and Happy Life (1962)
• The Names and Faces of Heroes (1963)
• A Generous Man (1966)
• Love and Work (1968)
• Permanent Errors (1970)
• Things Themselves (1972)
• The Surface of Earth (1975) (part one of the A Great Circle trilogy of novels aka The Mayfield Trilogy)
• Early Dark (1977)
• A Palpable God (1978) (translations from the Old and New Testaments, with an essay on the origins and aims of narrative)
• The Source of Light (1981) (part two of the A Great Circle trilogy)
• Vital Provisions (poems, 1982)
• Mustian (1983)
• Private Contentment (a 1984 television play)
• Kate Vaiden (1986)
• The Laws of Ice (poems, 1986)
• A Common Room (1987)
• Good Hearts (1988)
• Clear Pictures (his 1989 memoir)
• The Tongues of Angels (1990)
• The Use of Fire (poems, 1990)
• New Music (a 1990 trilogy of plays)
• The Foreseeable Future (stories, 1991)
• Blue Calhoun (1992)
• Full Moon (a 1993 play)
• The Collected Stories (1993)
• A Whole New Life (1994 memoir describing his survival of spinal cancer that started in 1984 and left him a paraplegic)
• The Promise of Rest (1995) (part three of the A Great Circle trilogy)
• Three Gospels (1996) (contains Price's translations of the Gospels of Mark and John, with introductory essays)
• The Collected Poems (1997)
• Roxanna Slade (1998)
• Letter to a Man in the Fire: Does God Exist and Does He Care? (an epistolary essay, 1999)
• A Singular Family: Rosacoke and Her Kin (1999)
• Feasting the Heart (2000) (52 of the essays he regularly broadcasts on National Public Radio's news program All Things Considered [1])
• Learning a Trade: A Craftsman's Notebooks, 1955-1997 (2000)
• A Perfect Friend (Price's first children's book, 2000)
• Noble Norfleet (2002)
• A Serious Way of Wondering: The Ethics of Jesus Imagined (2003)
• The Good Priest's Son (2005)
• Letter to a Godchild : Concerning Faith (2006)
• Ardent Spirits: Leaving Home, Coming Back (2009 memoir about his time at Oxford University and his first three years teaching at Duke University)

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John Jacob Rhodes III, American politician, U.S. Representative from Arizona (1987–1993) died he was , 67.

John Jacob "Jay" Rhodes III  was a Republican Representative from Arizona's 1st congressional district. He was born in Mesa, Arizona  died he was , 67.

(September 8, 1943 – January 20, 2011)

 Youth and education

Rhodes' father and namesake also represented the 1st district. Rhodes graduated from the Landon School in Bethesda, Maryland (1961); graduated from Yale University in New Haven, Connecticut (1965) with an A.B., and from the University of Arizona College of Law in Tucson, Arizona with a J.D. (1968).
Rhodes joined the United States Army in 1968, served in Vietnam, and left as a captain in 1970. He was admitted to the Arizona State bar in 1968 and commenced practice in Mesa. Rhodes was a Republican district chairman (1972-1982), served on the Mesa Board of Education (1973-1976), and served with Central Arizona Water Conservation District (1983-1986).

While in Congress

Rhodes was elected to the 100th United States Congress and to the two succeeding Congresses (January 3, 1987-January 3, 1993), but was unsuccessful as a candidate for re-election in 1992 to the 103rd Congress. After his defeat, he remained in Washington, D.C.

Accident and death

Rhodes died on January 20, 2011 at the Veterans Administration Medical Center in Washington, D.C.. Rhodes had been treated for three fractured vertebrae he sustained in an automobile accident in October 2010. He was found unconscious ten days before his death and began suffering organ failure. He was survived by his wife, Jane, sons John, Taylor, Jeremy, and Arthur, and mother, Betty Rhodes.^[2]

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Sexy Cora, German pornographic actress, died from cardiac arrest she was , 23

Sexy Cora (born Carolin Ebert, civil name Carolin Wosnitza;was a German pornographic actress, model, and reality show participant died from cardiac arrest she was , 23.
Cora was born in Berlin. She was one of the participants of the 10th season of Big Brother Germany.^[4][5] Cora released two music singles after her Big Brother participation: "My Love – La, La, La" and "Lass uns kicken (Alles klar wunderbar)".^[6]

May 2, 1987 – January 20, 2011)[1][2]

Medical issues and death

Cora was hospitalized in 2009 after trying to break the world record for the number of fellatios performed in one day. She was trying for 200 men but was unable to pass 75.^[5]
Cora had a heart attack on January 11, 2011, during her breast enlargement surgery at a plastic surgery clinic in Hamburg. It was her sixth such operation. Minutes into the procedure, she went into cardiac arrest. She was moved to a local hospital and placed in a medically-induced coma for a week.^[7][5][8] Police investigated the clinic afterward for possible treatment errors.^[9] Cora died on January 20, 2011. Cora was married at the time of her death. Her husband was at her side at the hospital from January 11 to her death.^[2]
On January 21, the two doctors who performed the surgery on Sexy Cora were charged with negligent manslaughter.^[1] A statement from the clinic said the doctors were "extremely upset and deeply regret the death of patient C.W." and that they are giving "full and complete support" to authorities investigating her death.^[1]

Filmography

• 2009: Versaute Freizeit
• 2010: Be Famous
• 2011: Gegengerade - Niemand siegt am Millerntor!

Awards

• 2010: Venus Award: Best Amateur Actress Germany^[5]
• 2010: Venus Award: Best Toy Series International (Sexy Cora Toys / Orion)
• 2010: Erotixxx Award: Best Amateur Actress^[5]

Music singles

• 2010: "My Love – La, La, La"
• 2010: "Lass uns kicken (Alles klar wunderbar)"

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Gus Zernial, American baseball player (Athletics, Tigers, White Sox), died from heart failure he was , 87.

Gus Edward Zernialwas a Major League Baseball left-fielder and right-handed batter who played for the Chicago White Sox (1949–51), Philadelphia Athletics (1951–54), Kansas City Athletics (1955–57) and Detroit Tigers (1958–59) died from heart failure he was , 87.. He was billed as the "New Joe DiMaggio."

(June 27, 1923 – January 20, 2011)^[1] 


Nicknamed "Ozark Ike" after the popular comic strip character, Zernial was one of the most feared sluggers in the 1950s, joining hall of famers Mickey Mantle, Yogi Berra and Larry Doby in the American League, for most home runs in the decade.
After he hit 29 homers for the White Sox in 1950, Zernial was sent to the Athletics in a trade that brought Minnie Miñoso to Chicago in 1951. That year Zernial led the league in home runs (33), runs batted in (129), extra base hits (68), and 17 assists in the outfield. In 1952 he hit 29 homers with 100 RBI, 42 and 108 in 1953.
Zernial was the first Major Leaguer to hit four home runs in the month of October during the regular season, which he accomplished during a doubleheader on October 1, 1950. In 1985, Ron Kittle would become the second player to do this.
Zernial and Al Zarilla and teamed up in April 1951 to become the only players whose last names started with "Z" to play together in the same outfield. Zernial and Zarilla and played left and right field, respectively, as part of a White Sox outfield unit in four games before Zernial was traded to the Philadelphia A's at the end of April.
An aggressive fielder, Zernial twice broke his collarbone while making a diving catch (1949 and 1954). He finished his career in Detroit, primarily as a pinch hitter, hitting .323 with 10 home runs in his new role.
Gus Zernial was a career .265 hitter (1093-for-4131) with 237 home runs, 776 RBI, 572 runs, 159 doubles, 22 triples, and 15 stolen bases in 1234 games.
Before being called up to the major leagues, Zernial played in the Pacific Coast League, the highly successful minor league circuit. In the HBO series When It Was a Game, Zernial states that he took a pay cut to come to the majors.
Zernial has the second most home runs of all time among players whose last name begins with the letter Z. His 237 are second only to Todd Zeile who finished his career with 253.^[2]
Zernial was diagnosed with cancer in 1990.
Mr. Zernial died at a Fresno hospice care center from the effects of congestive heart failure, said his daughter, Lisa Pearlstein.
"When my dad passed away he had his entire family around him," Pearlstein said. "For the past year he'd been in and out of the hospital quite a bit. But he fought the whole way."
Read more: http://www.fresnobee.com/2011/01/20/2240708/former-major-leaguer-gus-zernial.html#ixzz1CRcy2pbY^{[citation needed]}
When the Oakland Athletics played the Philadelphia Phillies for the first time in interleague play in June 2003 at Veterans Stadium, the Phillies invited former-Philadelphia A's Eddie Joost and Zernial to the games and recognized them prior to the first game.^[3]
Zernial recently served as a good-will ambassador with the Fresno Grizzlies (SF Giants PCL affiliate).
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Neva Egan, American First Lady of Alaska (1959–1966, 1970–1974), widow of William Allen Egan died she was , 96

Desdia Neva Egan  was an American educator who served as the first First Lady of Alaska from the state's creation in 1959 to 1966, and again from 1970 to 1974.^[1] Egan was the wife of the state of Alaska's first governor, William Allen Egan, and the mother of former Juneau Mayor and Alaska State Senator Dennis Egan.^[2]

(October 3, 1914 - January 19, 2011)

Biography

Early life

Egan was born Desdia Neva McKittrick on October 3, 1914, in Wilson, Kansas.^[3][1] She was the third of five children born to Joseph Leland McKittrick and Martha Desdia Alderson McKittrick.^[3][1] McKittrick worked at her family's grocery store to earn the tuition money to attend Kansas State College.^[1] She then transferred to the University of Wyoming, where her aunt was a faculty member, in Laramie, Wyoming.
McKittrick began her career teaching music in a public school in Glenrock, Wyoming, for two years.^[1] She was paid a salary of $1,000 USD annually.^[1] She moved to the Territory of Alaska from Wyoming in 1937.^[2] McKittrick sailed to Alaksa onboard a steamship called the Teachers Special, which brought teachers to Alaska to work in the territory during the winter.^[3] McKittrick moved to Valdez, Alaska, where she became one of just three new teachers hired for the Valdez school district that year^[1] for a one-year teaching assignment. ^[2] She taught fourth through sixth grader, as well as music, in the Valdez public school system.^[3]
McKittrick soon met her future husband, William Allen Egan, in Valdez, and the couple married on November 16, 1940.^[3] William Egan was also elected to the Alaska Territorial House of Representatives in 1940.^[3] William and Neva also operated a small grocery store, the Valdez Supply.^[3]

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